Huge production of highly polluting palm oil mill effluent(POME) has resulted serious environmental hazards. Anaerobic digestion is widely accepted as an effective method for treatment of POME. Nevertheless, anaerobic treatment of POME alone could hardly produces effluents that comply with effluent discharge limit. Hence, subsequent post treatment of aerobic treatment is vital. The objective of present study is to investigate the aerobic treatment of anaerobically digested POME by using sequencing batch reactor(SBR) in order to produce treated effluent which complies with the effluent discharge standard. A lab-scale SBR was utilized as it is simple, cost-saving and attainable without the risk of compromising effluent quality. The effects of mixed liquor suspended solids(MLSS) and organic loading rate(OLR) on chemical oxygen demand(COD) and total suspended solids(TSS) removal efficiencies were evaluated. In this study, OLR was gradually increased from 0.77 to 2.39kgCOD/m3.d, with feed COD concentration ranging from 5000 to 20000mg/L. MLSS level of the SBR was increased from 3000 to 15000mg/L. pH and dissolved oxygen concentrations were found to be 8.31-8.88 and 2.4-4.5mg/L, respectively throughout the experiment. The highest COD and TSS removal was 97% and 98% respectively, corresponding to MLSS level of 15,000mg/L, at OLR of 0.77kgCOD/m3.d and hydraulic retention time(HRT) of one day. The results indicated that COD and TSS removal efficiencies increased with increasing MLSS level. Conversely, increase in OLR had led to deterioration in treatment efficiency. Thus, MLSS level and OLR are governing parameters which will determine the performance of SBR in aerobic treatment of anaerobically digested POME.